Lipotoxicity & insulin resistance caused by saturated and transfatty acids

2015-10-31 09.36.38 am

“High SFA and TFA intake, the typical dietary pattern of western populations, favors a pro-inflammatory status that contributes to development of insulin resistance. Roles for SFA and TFA intake have been demonstrated in several inflammatory pathways and result from imbalances in the highly interconnected lipid signaling pathways that contribute to disease progression in chronic inflammation, auto-immunity, allergy, cancer, atherosclerosis, hypertension, and heart hypertrophy as well as metabolic and degenerative diseases.”

2015-10-31 09.40.46 am

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